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PurTox Neurotoxin Injection

   

                           

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PurTox like BOTOX with it being made from a strain of Type A botulinum toxin. PurTox is not as yet approved by the US FDA, and is currently in phase 3 testing for glabellar lines as well as medical/therapeutic indications. It is anticipated that PurTox will be used to treat facial lines and wrinkles that result from underlying muscle activity much like BOTOX.  

PurTox gets its name because the company finds it “pure” with not having any surrounding hemagglutinin protein complex.  PurTox, like Dysport and Xeomin has a higher concentration of human serum albumin.  The studies are still being conducted on this new toxin, and so far the efficacy, safety and longevity all appear to be very similar to BOTOX.  From the studies done so far, PurTox seems to show a slightly earlier onset when compared to BOTOX.

Puretox, a third competitor to BOTOX, is expected to hit the market in the spring of 2010.

PurTox is a botulinum toxin type A cosmetic injectable that reduce the appearance of facial wrinkles.  PurTox restricts muscle action that result in facial creases or wrinkles.  PurTox is pending approval from the United States FDA.  Mentor Corporation is the manufacturer of PurTox.

 

 

Onset of action of PurTox according to the Phase 3 studies going on is seen at day 3 with a follow up extended to 180 days.  In the Phase 2 studies the patients were injected with 30 units in the glabellar lines and the PurTox showed 100% efficacy at 30 days.  At 120 days the efficacy dropped to 50 percent.  With data using 20 units and also 10 units of PurTox showed that it might be slightly less effective than with BOTOX.

 

 

  • Side Effects - Advantages and Disadvantages of PurTox:

 Side Effects of PurTox:

  • Hypersensitivity to the active substance Botulinum neurotoxin type A.

  • Generalized disorders of muscle activity (myasthenia gravis, Lambert-Eaton syndrome).

  • Presence of infection at the proposed injection site.

 

ADVANTAGES & DISADVANTAGES OF PURTOX

  • PurTox has shown to have a quicker onset of action than BOTOX, and also has fewer antigens - which can lead to a possible resistance to the product.

  • All the advantages and disadvantages of the aesthetic use of PurTox are not known at this time.

 

 

 

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