manufactured by Isolagen Technologies Incorporated. Isolagen
is often called "grow-your-own-facelift”, and the generic name is cultured autologous human fibroblasts. This product is not FDA
Approved yet and is made by Isolagen.
The anti-aging skin care treatment is
designed to erase signs of wrinkles on your face, as well as to minimize scars
from acne. Isolagen is also used to augment lip shape and size.
In contrast to
other popular facial fillers such as some of the
hyaluronic acid products, which
offer quick repair - Isolagen is a more involved process. Isolagen requires the
growth of your own collagen in a lab; once prepared, it is injected into your
skin over a few weeks to fill in lines, wrinkles, and scars.
is extremely expensive and can cost anywhere from $5000 to $7500 depending on
the area being treated.
consists of cultured autologous fibroblasts. A 3-mm punch biopsy is obtained
from the patient and then sent to the manufacturer to be grown in culture. The
presence of growth factors used to culture the cells requires it to be regulated
by the FDA; therefore, for now, the company has temporarily halted production
and is not accepting biopsy samples from new patients.
Clinical trials are
underway that may eventually lead to FDA approval. Processing usually takes 6
weeks at which time a test dose is sent back to the physician to be administered
to the patient. If no reaction occurs after 2 weeks, Isolagen can be
to be injected into multiple levels of the dermis for best results in the
treatment of wrinkles and scars and for use in lip augmentation. Once received,
the product must be administered within 24 hours, which can be a logistic
challenge and an expensive waste if a patient or a physician cannot meet these
time constraints. Two to three treatments have been shown to yield persistent
therapeutic results for as long as 22 months.
ADVANTAGES AND DISADVANTAGES OF ISOLAGEN
biggest advantage to collagen based fillers is that it consists mainly of your
own collagen producing cells (fibroblasts) – rather than just collagen. If the
injected fibroblasts take hold in the treated area of your skin, they can keep
producing collagen for a long time. There is also no problem with rejection with
drawback with Isolagen is its cost factor along with the fact since it is still
relatively new, it may take some time before we know if its durability and
variability of results among individuals.